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Erectile dysfunction (ED), sometimes known as impotence, is the inability to get or maintain an erection firm enough for satisfactory sexual intercourse. ED can be temporary or ongoing, and while it can affect men of any age, it’s particularly common in older men.
The main causes of erectile dysfunction are typically physical conditions that affect blood flow to the penis or nerve function. These include cardiovascular disease, diabetes, high blood pressure, obesity, and hormonal imbalances like low testosterone. Psychological factors such as stress, anxiety, and depression can also contribute [1]. Many cases involve a combination of physical and psychological factors working together.
[1] Source: PMC – Association of Sexual Health and Mental Health in Erectile Dysfunction
The main NHS-approved treatments are PDE-5 inhibitor medications that work by increasing blood flow to the penis. These medications, including sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra), inhibit the enzyme phosphodiesterase, which normally ‘turns off’ an erection. This allows the body’s natural mechanisms to achieve and maintain an erection when sexually aroused.